Sofosbuvir/Velpatasvir (Generic Epclusa)
Sofosbuvir and Velpatasvir is a pan-genotypic combination that is prescribed for the treatment of hepatitis. Epclusa is a combination of an NS5A inhibitor (velpatasvir), and a nucleotide analog (sofosbuvir), which interferes with the synthesis of NS5B polymerase. The universal remedy was released in 2016 by the American developer Gilead Sciences.
The effectiveness and safety of a new antiviral medication were confirmed by medical tests of the ASTRAL series. They were attended by over “15,000 people”, including patients with compensated cirrhosis. According to the practical results, Epclusa Tablet can be included in the treatment of absolutely all genotypes of HCV. In addition, patients with and without cirrhosis may not take Ribavirin, which in combination with other medicines often causes adverse reactions.
Instructions for use:
The manual Sofosbuvir/Velpatasvir a contains useful information about universal antiviral medication. It can be used as a monopreparation during the treatment of interferon-free therapy in patients with compensated cirrhosis, as well as in combination with Ribavirin in the treatment of patients with decompensated cirrhosis. With a “12-week course of treatment”, a sustained virological response is achieved in 96–99% of cases.
Composition and indications for use:
Epclusa Tablet is available as an oral. They consist of two active components – sofosbuvir (400 mg) and velpatasvir (100 mg). The drug and its protective film coating contains additional inactive components – cellulose, copovidone, talc, iron oxide, magnesium and sodium croscarmellose stearate, titanium dioxide and polyvinyl alcohol.
Features of use and dosage:
In the absence of cirrhotic processes in the liver, “Sofosbuvir Velpatasvir India take 1 tablet per day before or after eating food. Chewing or crushing tablets is undesirable. During oral administration, they are washed down with plenty of water. Patients with decompensated cirrhosis should take tablets together with Ribavirin at the same time of day.
Special situations and contraindications:
In some cases, medical action can harm the patient. Such situations are possible when using a combination of Sofosbuvir/Velpatasvir.
This drug is contraindicated:
- minor patients (age up to 18 years);
- women at any stage of pregnancy;
- Patients with decompensated liver cirrhosis or severe renal failure.
Sofosbuvir and Velpatasvir Side effects:
Before conducting interferon therapy is recommended to check the function of the kidneys and liver. As a rule, the drug is well tolerated by patients. But in combination with Ribavirin, it can cause side effects:
- allergic rash;
- itching and flaking of the skin;
- Iron-deficiency anemia;
- sleep disturbance;
- decreased appetite;
How much price Sofosbuvir and Velpatasvir Online Cost and availability?
You can buy Online Velpatasvir in India with the best quality. Sofosbuvir Velpatasvir price in India is quite very affordable compared to other countries China, USA, Russia, Romania, Malaysia, Thailand & many more. There are several online pharmacies but before buying you should be assured about the company reviews and should be licensed.